Fluphenazine decanoate dosing is which of the following?

• A. 50-200 mg or 10-15x PO dose
• B. 12.5-50 mg
• C. 150-300 mg
• D. 100-200 mg

Answer: (A)

Fluphenazine decanoate is a long-acting injectable, so the amount given in a single shot is much larger and acts over a longer period than daily oral doses. The usual plan is to deliver a per‑injection dose in the range of about 50 to 200 mg and space injections about every two weeks. When converting a patient from oral fluphenazine to the depot form, clinicians often use a rough guide of roughly 10–15 times the patient’s daily oral dose. This combination—50–200 mg per injection, every 2 weeks, and using a 10–15× oral-dose conversion—explains why that option is the best fit.