Which describes physical irregularities that may be present in individuals with schizophrenia?

• A. Depressive symptoms prevalence
• B. Left-right confusion
• C. Minor physical anomalies of the face and limbs
• D. Onset of schizophrenia

Answer: (C)

Schizophrenia is thought to involve neurodevelopmental disturbances that can leave subtle physical signatures. Minor physical anomalies of the face and limbs are such signatures—small, nonspecific deviations from typical development that are more common in people with schizophrenia than in the general population. These features reflect prenatal or early-life developmental perturbations and help explain why this option best describes physical irregularities that may be present. In contrast, depressive symptom prevalence refers to mood symptoms, left–right confusion is a cognitive/perceptual issue, and onset timing describes when the illness appears, not physical irregularities.